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Mark Ratcliffe, M.D.

Mark Ratcliffe, M.D.

Professor of Surgery
Division of Adult Cardiothoracic Surgery, UCSF
Co-Director, Cardiac Biomechanics Lab

Contact Information

4150 Clement Street
San Francisco, CA  94121
tel: 415-750-2057
fax: 415-750-2181

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  • M.D.-Case Western Reserve University, Cleveland, OH
  • B.A. - Denison University, Granville, OH
  • Internship - John Hopkins Hospital, Baltimore, MD
  • Residency - John Hopkins Hospital, Baltimore, MD
  • Residency - University of Pennsylvania Hospital, Philadelphia, PA
  • Research Fellow - University of Pennsylvania Hospital, Philadelphia, PA
  • Fellowship - University of Pennsylvania Hospital, Philadelphia, PA
  • American Board of Surgery, 1989
  • American Board of Thoracic Surgery, 1993
  • Minimally invasive cardiac surgery
  • Off-pump coronary artery bypass surgery
  • Robotic surgery
  • Surgery for heart failure
  • Thoracic aortic surgery
  • Valve repair and replacement
  • Finite element analysis of failing left ventricle

Dr. Ratcliffe received his M.D. degree from Case Western Reserve School of Medicine and completed his General Surgery and Cardiothoracic residencies at the Univeristy of Pennsylvania. Dr. Ratcliffe is certified by the American Board of Surgery and American Board of Thoracic Surgery. His special interest is in the application of finite element analysis or the failing left ventricle. Dr. Ratcliffe has been on the faculty since 1993. Currently, he is Director of the Cardiac Biomechanics Laboratory.

Dr. Ratcliffe is an active member of the American Society for Artificial Internal Organs, American Heart Association, Society of Thoracic Surgeons, Western Thoracic Surgical Association, San Francisco Surgical Society, American Association of Thoracic Surgery, and is a Fellow of the American College of Surgeons.

Data provided by UCSF Profiles, powered by CTSI
  • Quantitative analysis of left ventriculoplasty: CHF
    Sponsor ID:
    Funding Period:
    Apr 2000
    Apr 2018
    Principal Investigator
  • Surgery for Ischemic Mitral Regurgitation
    Sponsor ID:
    Funding Period:
    Jan 2008
    Dec 2013
    Principal Investigator
Data provided by UCSF Profiles, powered by CTSI
  1. Wang VY, Tartibi M, Zhang Y, Selvaganesan K, Haraldsson H, Auger DA, Faraji F, Spaulding K, Takaba K, Collins A, Aguayo E, Saloner D, Wallace AW, Weinsaft JW, Epstein FH, Guccione J, Ge L, Ratcliffe MB. A kinematic model-based analysis framework for 3D Cine-DENSE-validation with an axially compressed gel phantom and application in sheep before and after antero-apical myocardial infarction. Magn Reson Med. 2021 10; 86(4):2105-2121. View in PubMed
  2. Zhang Y, Wang VY, Morgan AE, Kim J, Tafreshi R, Wallace AW, Guccione JM, Weinsaft JW, Ge L, Ratcliffe MB. Finite-element based optimization of left ventricular passive stiffness in normal volunteers and patients after myocardial infarction: Utility of an inverse deformation gradient calculation of regional diastolic strain. J Mech Behav Biomed Mater. 2021 07; 119:104431. View in PubMed
  3. Kochav JD, Kim J, Judd R, Kim HW, Klem I, Heitner J, Shah D, Shenoy C, Farzaneh-Far A, Polsani V, Kalil R, Villar-Calle P, Nambiar L, Sultana R, Parker M, Cargile P, Khalique OK, Leon MB, Karmpaliotis D, Ratcliffe M, Levine R, Zoghbi WA, Devereux RB, Moskowitz CS, Kim R, Weinsaft JW. Ischemia-Mediated Dysfunction in Subpapillary Myocardium as a Marker of Functional Mitral Regurgitation. JACC Cardiovasc Imaging. 2021 04; 14(4):826-839. View in PubMed
  4. Morgan AE, Kashani A, Zenger B, Rupp LC, Perez MD, Foote MD, Morris AK, Ratcliffe MB, Kim JJ, Weinsaft JW, Sharma V, MacLeod RS, Elhabian S. Right Ventricular Shape Distortion in Tricuspid Regurgitation. Comput Cardiol (2010). 2020 Sep; 47. View in PubMed
  5. Giao DM, Wang Y, Rojas R, Takaba K, Badathala A, Spaulding KA, Soon G, Zhang Y, Wang VY, Haraldsson H, Liu J, Saloner D, Guccione JM, Ge L, Wallace AW, Ratcliffe MB. Left ventricular geometry during unloading and the end-systolic pressure volume relationship: Measurement with a modified real-time MRI-based method in normal sheep. PLoS One. 2020; 15(6):e0234896. View in PubMed
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